Functional pharmacogenetics: Analysis of the functional effect of the IL28B genotype on hepatitis C virus infection and treatment response.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1018079

Funding Status
Closed

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Funded Activity Summary

An estimated 3% of the world�s population is infected with hepatitis C virus (HCV). With low spontaneous clearance rates and often a poor response to treatment many infected individuals will develop long term complications from HCV. Recent studies have identified a genetic variant that is significantly associated with spontaneous viral clearance of HCV and response to treatment for HCV. We propose to further investigate the functional basis for the effect of this human genotype on drug response.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $93,843.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunogenetics (incl. Genetic Immunology)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

hepatitis C infection | interferon (IFN) | interferon non-responders | single nucleotide polymorphism (SNP)

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