Rapid HIV-1 tropism testing using novel, soluble mimics of the HIV-1 coreceptors CCR5 and CXCR4

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1017752

Funding Status
Closed

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Funded Activity Summary

This proposal seeks to develop an inexpensive assay to determine whether HIV patients will benefit from treatment with new drugs referred to as CCR5 antagonists. These are effective against HIV strains that use the CCR5 coreceptor, therefore a patient�s HIV coreceptor usage must be assessed before commencing therapy. Current assays are complicated, slow and expensive. Using novel, soluble mimics of the coreceptors we will develop an ELISA based test that can be operated using standard equipment.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2012

Funding Scheme: NHMRC Development Grants

Funding Amount: $163,426.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Microbiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

ELISA | antibiotics | chemokine receptor | human immunodeficiency virus (HIV)

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