Development of Platelet-Targeted Nanoparticles for Magnetic Resonance Imaging towards the Detection of Thrombi/Emboli and Vulnerable Atherosclerotic Plaques

Funding Activity

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Funded Activity Summary

Heart attack, stroke and pulmonary embolism typically strike without warning and either kill patients or cause devastating disabilities. Currently, we do not have diagnostic methods to identify patients and the blood vessels at risk. We have developed a new innovative MRI nanoparticle directed against activated platelets for the detection of _at risk� blood vessels. The current funding is requested to optimise the manufacture of this targeted MRI nanoparticle and to undertake the animal studies required to enter early stage clinical trials.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Development Grants

Funding Amount: $606,524.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

inflammation | magnetic resonance imaging (MRI) | myocardial infarction | nanotechnology | plaque rupture | platelets | pulmonary embolism | stroke | thrombosis | vascular occlusion