Cellular and molecular aspects of mammographic density as a predictor of breast cancer risk in pseudo-orthotopic mammatrophic environment

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1017421

Funding Status
Closed

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Funded Activity Summary

High mammographic density (MD), or denser breast tissue on mammogram, is associated with greater breast cancer risk. Despite this, the basis for its increased risk is poorly understood. This study assesses the effect of high density breast tissue transferred from high risk women at time of mastectomy into tissue engineering chambers in mice. Changes in the connective tissue harvested from the chamber were examined with specialized imaging, laboratory stains and molecular analysis.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $113,322.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

breast cancer | breast cancer aetiology | breast cancer prevention | breast carcinoma | extracellular matrix | mammography | tissue engineering

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