Regulation of extrinsic death pathways in neutrophils

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1017387

Funding Status
Closed

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Funded Activity Summary

During infection, the lifespan of neutrophils normally increases despite an abundance of neutrophil death signals in inflamed tissues. Altered lifespan of neutrophils has been reported in diseases associated with influenza, Streptococcus, RSV and cytomegalovirus infection. Our research has discovered a relationship between the two dominant death pathways in neutrophils, indicating that alterations in one death pathway protect the neutrophil from death signals from the second death pathway.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Postgraduate Scholarships

Funding Amount: $84,656.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

apoptosis | arthritis | chronic inflammation | cytokines | infection | inflammation | neutrophils | sepsis

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