Pathogenesis of vascular shock and platelet dysfunction in sepsis: the role of calcium desensitization, statins and cortisol.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1017330

Funding Status
Closed

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Funded Activity Summary

Severe infections are characterised by a profound drop in blood pressure, which starve vital organs of oxygen and nutrients, this �septic shock� can lead to organ failure and death. We aim to identify dysfunction of the molecular signals in blood vessels, which leads to the failure of these vessels to maintain adequate blood pressure. Understanding the mechanisms regulating blood pressure during septic shock will enable us to develop therapies to support the circulation and reduce the significant death toll from life threatening sepsis.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $89,778.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Physiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

critical care medicine | sepsis | shock | smooth muscle abnormality | vascular biology

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