Element labeling antibodies for bio-imaging of proteins: a case study of beta-amyloid in Alzheimer's disease mouse models

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1016737

Funding Status
Closed

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Funded Activity Summary

This project will develop new analytical methods for quantitative in-situ imaging of beta-amyloid in mouse brains. Beta-amyloid deposition in the brain is associated with Alzheimer�s disease. It is also planned to simultaneously image metal ions, which are also implicated in the deposition of beta-amyloid. Application of these novel methods to Alzheimer�s disease mouse models will provide new knowledge and significant insights into the aetiology of Alzheimer�s disease by determining the relationship between amyloid proteins and metal ions.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2012

Funding Scheme: Early Career Fellowships

Funding Amount: $221,136.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biologically Active Molecules

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alzheimer disease | imaging | mass spectrometry | metals

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