Developing new therapies to combat tuberculosis through inhibition of vitamin B5 metabolism in the organism that causes the disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1016357

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

The metabolism of vitamin B5 by pathogenic microorganisms has been recognised as an attractive target for developing drugs to combat various infectious diseases. The aim of the proposed work is to develop inhibitors of vitamin B5 metabolism in the bacterium that causes tuberculosis, using a powerful, multidisciplinary approach known as “fragment-based drug discovery”. This work is likely to yield potent inhibitors of the target bacterium, which could ultimately be used to treat tuberculosis.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2017

Funding Scheme: Early Career Fellowships

Funding Amount: $311,760.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Mycobacterium tuberculosis | chemotherapy | drug discovery | enzyme inhibition | infectious diseases | multidisciplinary | novel therapeutic agents | structure-based drug design | tuberculosis

Related Links