Exploring the pluridimensionality of drug efficacy.

Funding Activity

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Funded Activity Summary

Dysfunction of cell surface receptors is the underlying cause of many pathological conditions. Using cell based screening methods we aim to investigate the mechanisms underlying drug action, to understand how drugs acting at common targets promote distinct biological responses. This will aid the development of new therapeutics based on the ability to predict specific drug effects.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2018

Funding Scheme: Early Career Fellowships

Funding Amount: $326,184.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

G protein-coupled receptors | beta-adrenoceptor subtypes | cardiovascular disease | drug design | drug efficacy | efficacy | heart disease | muscarinic receptors | signalling pathways | tolerance