Induction of Islet Transplant Tolerance in a Humanised Mouse Model

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1013185

Funding Status
Closed

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Funded Activity Summary

The current treatment for type 1 diabetes (T1D) is insulin therapy, but it cannot fully prevent chronic complications. Also intensive insulin use increases the risk of fatal hypoglycemia. An emerging therapy which may overcome or at least reduce these problems is the transplantation of human islet cells. But preventing the immune system from rejecting these cell transplants is still a major challenge. This study will develop new therapeutic strategies to protect these transplants from rejection.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2015

Funding Scheme: Early Career Fellowships

Funding Amount: $374,552.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cell immunotherapy | diabetes | end organ damage | human-mouse chimeras | islet transplantation | transplantation tolerance

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