TGFB1 is a pivitol regulator of endometriotic lesion development

Funding Activity

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Funded Activity Summary

Endometriosis occurs when the tissue that lines the womb is found in the pelvic cavity. 10% of reproductive aged women have endometriosis and suffer from debilitating pelvic pain and subfertility. We have shown that transforming growth factor (TGFB1) is central to the growth of endometriosis and that its absence suppresses disease development. We hope to clarify the role of TGFB1 in endometriosis, in order to develop better therapeutic options for women incapacitated by this disease.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $438,749.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Obstetrics and Gynaecology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bioinformatics | clinical patient management | dysmenorrhoea | endometriosis | infertility | microrna | mouse models | pelvic pain | sexual dysfunction