Characterisation of T-cell Responses in Drug Hypersensitivity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1012608

Funding Status
Closed

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Funded Activity Summary

Drug hypersensitivity reactions (DIHS) are a catastrophic form of adverse drug reaction. This study will use the drug abacavir, a cause of drug hypersensitivity to examine the way certain immune cells react and determine whether responses to viruses that are persistent in our bodies play a role these development of these reactions. This will help inform the immunological basis of DIHS as well as new treatments and potential ways of identifying drugs likely to cause these reactions in the pre-marketing phase of drug development.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: Project Grants

Funding Amount: $306,338.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adverse drug reactions | hypersensitivity | immunogenetics | immunopathogenesis | lymphocytes

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