Kinetics, mechanism and engraftment of in vitro generated T cell precursors as a strategy to enhance thymic rejuvenation following allogeneic hematopoietic stem cell transplantation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1012401

Funding Status
Closed

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Funded Activity Summary

Immune regeneration - following standard cancer therapies such as chemotherapy and radiation-therapy for hematopoietic (blood) stem cell transplant (HSCT) - is one of the most significant unmet clinical challenges today. This research will focus on using “off the shelf” precursor T cells to improve immune reconstitution following HSCT, thereby significantly reducing the incidence of morbidity and mortality following transplantation.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2017

Funding Scheme: Early Career Fellowships

Funding Amount: $403,324.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Transplantation Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cell development | bone marrow | haematological malignancy | lymphocyte differentiation | radiation therapy | stem cell transplantation | thymus

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