Linking breast development to bone metastasis: Role for the osteogenic transcription factor Runx2 during breast carcinogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1012282

Funding Status
Closed

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Funded Activity Summary

Bone is the principle metastasis site of breast cancer and represents a major cause of morbidity and mortality. Runx2 is one potential candidate gene mediating breast cancer metastasis. Using mice with altered Runx2 levels and breast cancer models, this study will examine the role of Runx2 in breast cancer bone metastasis. Identification of a single gene that controls both breast and bone would open a new area of breast cancer research and a new gene against which therapies could be developed.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: Project Grants

Funding Amount: $565,145.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bone metastasis | breast cancer | breast cancer metastases | cancer progression | cancer treatment | carcinogenesis | transcription factor

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