Macrophages: a therapeutic target in peritoneal dialysis-induced fibrosis?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1012009

Funding Status
Closed

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Funded Activity Summary

Fibrosis (scar tissue) in the abdominal cavity is a common side-effect of peritoneal dialysis (a treatment for kidney failure), and results in a life-threatening loss of dialysis function. The cells causing the fibrosis are uncertain. This project asks: Are inflammatory cells (macrophages) the source of peritoneal scar tissue? What regulates the fibrotic process? Answers may lead to strategies to prevent fibrosis induced by peritoneal dialysis, abdominal surgery or other causes.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: Project Grants

Funding Amount: $593,888.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

abdominal surgery | angiogenesis | fibrosis | macrophages | myofibroblast | peritoneal dialysis | renal failure

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