Evolution of pertussis epidemics and effect of genotypes on infection outcomes and immunisation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1011942

Funding Status
Closed

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Funded Activity Summary

Pertussis, or whooping cough, is caused by Bordetella pertussis. Despite high vaccine coverage, the incidence of pertussis has increased substantially in recent years in Australia. One of the contributing factors is changes in the pertussis strains. This project will determine the genetic composition and virulence characteristics of epidemic strains in Australia and investigate the effect of these strains on disease severity and vulnerability of vaccinated individuals to infection.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $657,781.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

genomics | infectious diseases | molecular epidemiology | pertussis | vaccine-preventable diseases

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