Understanding new drug paradigms at M1 muscarinic receptors.

Funding Activity

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Funded Activity Summary

The M1 muscarinic receptor is a brain protein that plays vital roles in memory, and has been implicated in Alzheimer�s and schizophrenia. However, this protein remains poorly targeted by current medications. The current proposal will investigate the mechanisms of action of a new class of more selective M1 receptor drugs. Our studies will generate valuable information that is directly relevant to the pharmaceutical industry and academic drug discovery.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $334,053.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alzheimer disease | G protein-coupled receptors | central nervous system (CNS) | drug discovery | molecular pharmacology | muscarinic receptors | pain | schizophrenia and related disorders | signal transduction