Deciphering mechanisms of liver allograft tolerance

Funding Activity

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Funded Activity Summary

The liver has paradoxical properties: it is the site of effective immune responses to pathogens, but under some circumstances, it is known to induce harmless immune responses. Liver transplants are more readily accepted than other organ grafts in the absence of immunosuppressive drugs but little is known about the mechanisms that prevent an effective response. This proposal aims to unravel these mechanisms. This project will have important implications for transplantation studies.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $520,964.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Transplantation Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cells | apoptosis | graft rejection | hepatitis | hepatocytes | liver | liver disease | liver injury | transplantation tolerance