Targeting Drug-Resistance in Paediatric Acute Lymphoblastic Leukaemia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1011499

Funding Status
Closed

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Funded Activity Summary

Leukaemia is the most common type of cancer in children but resistance to therapy continues to be a significant problem. This project will investigate the biology of drug-resistance and relapse using a mouse model that replicates the human disease. We hope to identify novel therapeutic targets that can be used in combination with existing therapies to improve outcomes in this disease, particularly for patients that develop drug-resistance such as those at the time of relapse.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $649,048.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematological Tumours

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

NOD/SCID mouse model | acute lymphoblastic leukaemia (ALL) | drug resistance | microarray analysis | novel therapeutic agents | paediatric | relapse | xenografts

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