The impact of micropolymorphism within the T cell receptor genes and their target antigenic peptides

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1011498

Funding Status
Closed

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Funded Activity Summary

T lymphocytes play a pivotal role in the immune system by recognising virus-infected tissue through the use of highly specific T cell receptors (TCRs). This project will investigate the importance of genetic variation in the TCR genes in influencing how we fight infections. Another aim is to examine how the immune system tolerates genetic variation in an infecting virus. Advances in these areas will aid in the development of new "intelligent" vaccines.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: Project Grants

Funding Amount: $365,126.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Epstein-Barr virus (EBV) | T cell epitope | T cell immunity | T cell receptor | T cell response | cytotoxic T lymphocytes (CTL) | infectious diseases

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