Understanding the importance of lipid metabolism in mediating the anti-diabetic effects of metformin

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1011486

Funding Status
Closed

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Funded Activity Summary

Obesity is a major cause of adult onset Type 2 diabetes. This project is investigating the mechanism of action of the glucose lowering drug metformin on fat metabolism. We are investigating whether the regulation of two enzymes, involve in fat synthesis and the burning of fat respectively that are important for metformin�s action. Through this research we hope to improve on the treatment of Type 2 diabetes and cardiovascular disease.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $555,892.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

AMP-activated protein kinase | ageing | diabetes mellitus | lipid metabolism | obesity

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