Lymphangiogenesis from development to disease: Analysis of SOX18 function in the control of lymphatic remodeling

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1011242

Funding Status
Closed

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Funded Activity Summary

Cancers are lethal mainly because they spread (metastasise) to other parts of the body via blood vessels and lymphatic ducts. Pilot studies suggest that suppressing the function of a gene, SOX18, reduces tumour metastasis. We now propose to confirm these findings and study this effect in detail, with the ultimate aim of developing new therapies able to complement already existing anti-cancer treatments.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Career Development Fellowships

Funding Amount: $401,361.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Developmental Genetics (incl. Sex Determination)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer metastasis | developmental genetics | gene expression | lymphatics | metastasis suppressor | molecular genetics | mouse models | transcription factor

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