Activin and androgen crosstalk during testis development programs adult fertility

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1011192

Funding Status
Closed

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Funded Activity Summary

Fertility in men is determined by how the testis grows during fetal and juvenile life. We recently discovered that the Sertoli cells which nurse developing sperm are highly sensitive to cross-talk between testosterone and the growth factor activin during puberty. This project studies how this cross-talk is controlled to understand how altered hormone actions in boys, including exposure to harmful endocrine disrupting chemicals, reduces adult fertility.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $700,740.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Reproduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

activin | androgen-response | fertility | puberty | reproduction | signalling pathways | testis development

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