Targeting bone marrow mediated angiogenesis and metastasis in breast cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1011114

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Despite advances in treatment and diagnostics breast cancer (BC) remains one of the leading causes of death in women. Metastases and tumour blood vessel recruitment are linked. Work by Dr Mellick and others has shown that host bone marrow contributes endothelial progenitor cells (EPCs) to tumour vasculature. The chemokines and their receptors, which differentiate EPCs from tumour vessels, will be knocked down in the tumour cells and EPC progenitors with the aim of preventing tumour spread.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2017

Funding Scheme: Project Grants

Funding Amount: $463,006.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

RNA interference | angiogenesis | bone marrow | breast cancer | cancer | cancer cell biology | chemokines | molecular mechanisms | oncology

Related Links