Vasomotor ganglionic transmission: the preganglionic peptide and the second gear

Funding Activity

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Funded Activity Summary

Blood pressure depends on nerve signals that travel from the central nervous system to blood vessels. In the middle of this pathway is a relay station - the sympathetic ganglion cell. Transmission through this relay station has recently been shown to have not only a fixed but also a variable component - the 'second gear'. The project tests if and how three likely candidate peptide molecules, one in the nerves, two in the bloodstream, control this 'second gear' and hence regulate blood pressure.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $451,896.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autonomic Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

angiotensin II | autonomic function | autonomic ganglia | heart failure | hypertension | peptides | synaptic transmission