Cytokine structure and mechanisms of a superagonist antibody

Funding Activity

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Funded Activity Summary

Monoclonal antibodies are widely used in diagnosis and therapy due to their outstanding specificity and safety. The monoclonal antibodies recognizing cytokines with enhancing functions are an emerging class of novel reagents in immunotherapy. This project is to investigate how a newly indentified monoclonal antibody enhances the activity of a cytokine and use this immunostimulatory function to design new strategies for better vaccination and treatment for cancer and infection.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: Project Grants

Funding Amount: $349,590.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Immunology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antibody | cancer immunology | cancer immunotherapy | infection | interleukins (IL) | signalling pathways | structural immunology | vaccination