Helicobacter pylori VacA toxin: modulation of human mitochondrial function by a bacterial pathogen

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1010745

Funding Status
Closed

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Funded Activity Summary

This work will greatly further our understanding of how a bacterium, Helicobacter pylori, causes stomach ulcers and cancer. We will use cutting edge model systems to study the VacA toxin that is secreted from the bacteria and is targeted to human cells. We will examine where the toxin goes and how it affects our cells. It is expected that the improved understanding that will arise from this work will assist researchers to better devise drugs against this prevalent pathogen.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $508,003.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Helicobacter pylori | bacterial toxins | gastric cancer | gastric ulcers | pathogenesis | pathogenic bacteria | pathogenic mechanisms | toxins

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