Influence of in utero environment on diaphragm structure and function

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1010665

Funding Status
Closed

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Funded Activity Summary

The diaphragm is the major muscle involved in breathing. Normal function of the diaphragm is essential to survival. Preterm babies may be exposed to infection and other agents that interfere with diaphragm development and make breathing efforts weaker after birth, potentially leading to respiratory failure. This study will study diaphragms of preterm lambs to determine how fetal exposure to infection and steroids affect fetal diaphragm development, and if adverse effects are prevented by fetal treatment with blocking agents.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $494,966.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Systems Physiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

chorioamnionitis | diaphragm function | glucocorticoids | inflammation | muscle damage | muscle development | oxidative stress | premature | respiratory muscles

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