RNA-DIRECTED EPIGENETIC REMODELLING IN CANCER

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1010620

Funding Status
Closed

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Funded Activity Summary

Epigenetics describes how genes can be turned off or on without changing the DNA sequence. Epigenetics plays a major role in cancer development. In this proposal we are investigating a novel hypothesis that in cancer a similar mechanism to imprinting USING NON-CODING RNA is triggered and this promotes the suppression of clusters of genes. The results from this proposal will have major implications to our understanding of gene regulation in cancer and will have important therapeutic value for cancer treatment.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $718,770.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

basic science | cancer biology | cancer research | carcinogenesis | chromatin structure | epigenetics | gene expression | molecular basis of disease | prostate cancer

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