Characterisation of a novel PI3-kinase signal terminating enzyme in breast cancer.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1010430

Funding Status
Closed

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Funded Activity Summary

Breast cancer is the most common malignancy among females, affecting 1 in 9 women before the age of 85. Normally cells divide only when they receive a stimulus from a hormone or growth factor. The PI3K pathway which responds to these stimuli has been implicated in cancer where cells divide uncontrollably and invade surrounding tissue. We have identified a potential cancer suppressing gene, PIPP, which turns off PI3K growth signals. We aim to characterize the role of PIPP in breast cancer.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $633,512.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

breast cancer | breast cancer metastases | cancer staging | cell proliferation | phosphoinositide 3-kinase | prognostic markers | tumour growth | tumour suppressor

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