Long-term human response following subretinal injection of recombinant adenoassociated virus-sFlt-1 vector

Funding Activity

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Funded Activity Summary

Age-related Macular Degeneration (AMD) is the major cause of blindness in the developed world. The present best practice for treating wet AMD is monthly injections of Lucentis� into the eye which is expensive, inconvenient for the patient and has increased risk of infection. The additional assays associated with the clinical trial will test whether adeno-associated virus-mediated gene therapy is safe and whether it can eliminate the need of multiple injections while delivering the same outcome.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $373,076.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

gene therapy | immune response | immunology | macular degeneration | safety | vision