Memory CD4 T cells that harbour the reservoir of latent HIV infection: their antigen specificity, function and frequency of antigen-driven reactivation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1010185

Funding Status
Closed

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Funded Activity Summary

Current antiretroviral therapy for HIV successfully suppresses virus production, but does not completely eliminate the virus from the body. This project will provide essential information on memory CD4 T cells that retain HIV in a latent DNA form. Memory CD4 T cells can be very long-lived, and these latently infected memory cells can give rise to virus during treatment interruption. We will use a novel method to identify which memory CD4 T cells contain latent HIV DNA.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: NHMRC Project Grants

Funding Amount: $453,782.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cell memory | T cell subset | T cells | human immunodeficiency virus (HIV) | infectious diseases | viral immunity

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