KLK4 is a master regulator of tumour microenvironment remodelling in prostate cancer and bone metastasis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1010141

Funding Status
Closed

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Funded Activity Summary

The current biomarker for prostate cancer, PSA, belongs to a large family of related proteins called KLK enzymes. We have evidence that one of these enzymes, KLK4, regulates many different pathways involved in tumour spreading especially to bones. This project will determine the specific components involved with a view to finding better biomarkers of tumour spread and bone metastasis and designing better treatments for these aspects of the disease.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $596,305.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bioinformatics | biomarkers | bone metastasis | cancer biology | cancer prognosis | kallikreins | men's health | prostate cancer | proteomics | therapeutic target

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