A double-blind randomised controlled multi-site study of sertraline compared with placebo for refractory breathlessness

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1010065

Funding Status
Closed

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Funded Activity Summary

People with optimally treated emphysema often have breathlessness at rest or with little effort (dressing, preparing a meal). No medications are registered to reduce this breathlessness. This 3 year project will study whether a commonly used anti-depressant, sertraline, can reduce this breathlessness even if people are not depressed. Across Australia, 150 people will take part for at least 4 weeks to rate the unpleasantness of their breathlessness on sertraline or an identical sugar tablet.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $603,517.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

chronic obstructive pulmonary disease (COPD) | dyspnoea | palliative treatment | pharmacological intervention | respiratory failure | symptom reduction

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