How chromatin compaction is regulated and its link with disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1009851

Funding Status
Closed

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Funded Activity Summary

Chromosomes are constructed from very small particles called nucleosomes. How these nucleosomes interact with each other to build an entire chromosome is not known but elucidating this mechanism is critical in order to understand cancer when chromosomes become unstable. Furthermore, the strength of nucleosome-nucleosome interactions determines whether a gene is expressed or not. This study will elucidate the nature and the mechanism of how nucleosome-nucleosome interactions are regulated.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $493,747.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

basic science | cancer | chromatin structure | chromosomes | epigenetics | protein interactions

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