Structure-based design of inhibitors of oxidative protein folding in Enterobacteriaceae.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1009785

Funding Status
Closed

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Funded Activity Summary

Antibiotic resistance represents a major public health problem. For gram-negative bacteria in particular, the situation is increasingly bleak, with the accumulation of resistance to existing drugs and few if any new drugs in the pipeline. We are using structure-based drug design to develop novel strategies for the treatment of gram-negative bacterial infections.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $523,540.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bacterial infection | bacterial virulence | drug design | enzyme inhibition | medicinal chemistry | structure-based drug design

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