In-depth association and functional studies assessing the role of novel single nucleotide polymorphisms in PSA and other Kallikrein genes in prostate cancer.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1009458

Funding Status
Closed

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Funded Activity Summary

The number of men diagnosed with prostate cancer varies substantially between races, indicating a role of genetics in prostate cancer development. Recently, we demonstrated that the genetic variations in the PSA gene are related to prostate cancer risk. We aim to elucidate the molecular mechanism of this correlation and to systematically investigate the association of novel genetic variations in other PSA related genes with prostate cancer risk in a search of sensitive clinical biomarkers for prostate cancer diagnosis and prognosis.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $607,336.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Quantitative Genetics (incl. Disease and Trait Mapping Genetics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

aged health | cancer genetics | cancer screening | clinical genetics | gene polymorphisms | kallikreins | men's health | prostate cancer | sequencing

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