Selective serotonin re-uptake inhibitors (SSRIs) and osteoporosis: Mechanisms and clinical consequences

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1009367

Funding Status
Closed

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Funded Activity Summary

Selective serotonin re-uptake inhibitors (SSRIs) are commonly used to treat depression. Serotonin is not unique to the brain but is also used by other cells in the body, including bone cells. In this project the influence of SSRIs on human osteoclast and osteoblast formation and function will be investigated in a laboratory. Additionally, the impact of SSRI use on bone loss and fracture risk in a community sample of women and men will be investigated. These studies will determine if exposure to SSRIs adversely impact bone health.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $422,964.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Psychiatry (incl. Psychotherapy)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antidepressants | bone | mental health | psychiatric disorders | psychiatry

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