Mechanisms of nanoparticle-mediated inhibition of asthma

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1009354

Funding Status
Closed

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Funded Activity Summary

Ultrafine pollution particles may promote asthma, and there is concern that man-made 'nanoparticles' have a similar effect. Surprisingly, we found that inert toxin-free nanoparticles inhibit asthma. We propose nanoparticles do this by leaving a unique �imprint� in the lung. We will explore how this imprint modifies lung inflammatory and immune regulatory cell function, and investigate particles made from advanced biodegradable polymers as potential therapeutics for inflammatory lung diseases such as asthma.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $637,921.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nanomedicine

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

airway inflammation | allergen-induced inflammation | allergic airways disease | dendritic cell | nanotechnology | regulatory T cells

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