Identifying regulators of the DNA damage response and tumourigenesis using C. elegans

Funding Activity

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Funded Activity Summary

By the age of 85, one in two men and one in three women in Australia will develop cancer. Regrettably, not all cancers respond to current therapies. Recently a new mechanism that prevents certain cancers from responding to chemotherapy has been identified, involving a protein called HIPK. We are using a simple model system, the nematode Caenorhabditis elegans, to discover ways in which this block to successful cancer treatment can be overcome, with the view to developing new therapeutic agents.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $514,367.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Gene Expression (incl. Microarray and other genome-wide approaches)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA damage | apoptosis | cancer genetics | gene discovery | gene regulation | genetics