Manipulating cardiac-selective PI3K targets to reverse heart failure progression

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1009025

Funding Status
Closed

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Funded Activity Summary

Heart failure is a major clinical problem which is becoming worse as our population ages. New therapeutic strategies with the capability of improving function of the failing heart are greatly needed. We have identified novel targets of a gene with protective properties in the heart. This proposal will examine whether these new targets can reverse heart failure progression. Technologies that target these genes may lead to innovative pharmacotherapies in the clinical management of heart failure.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $532,921.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cardiac hypertrophy | cardiovascular disease | gene therapy | heart failure | mouse models

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