Respiratory viral infections as triggers of acute severe asthma exacerbations in atopics: mechanistic studies in an experimental model

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1008741

Funding Status
Closed

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Funded Activity Summary

An important unresolved issue in asthma research is why almost all the children who present in hospital emergency with very severe asthma attacks are both allergic and virally infected. This project will seek to define how immune responses to viruses and aeroallergens interact to create very severe inflammation in the airways thus precipitating the severest type of asthma attacks. Understanding the underlying mechanisms will hopefully provide new clues towards better treatments.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: NHMRC Project Grants

Funding Amount: $659,494.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Clinical Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cell activation | allergic asthma | asthma exacerbation | asthma severity | atopy | dendritic cell | respiratory infection

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