Microtubule cytoskeleton in tumourigenesis and metastasis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1008719

Funding Status
Closed

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Funded Activity Summary

Over one million cases of lung cancer are diagnosed each year worldwide, making this the leading cause of cancer death. Advanced non-small cell lung cancer (NSCLC) accounts for more than 80% of lung cancer cases. We have identified a protein called ?III-tubulin that is often highly expressed in aggressive and drug resistant NSCLC, and is involved in tumour formation. We will examine how ?III-tubulin is working and identify ways to target this protein to stop tumour growth.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $612,885.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

gene silencing | microtubules | non-small cell lung cancer | proteome analysis | solid tumours | tubulin | tumour aggression | tumourigenesis

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