Ancient proteins and disease.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1008667

Funding Status
Closed

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Funded Activity Summary

Most diseases are much more common in the elderly. The reasons are poorly understood. We have evidence that the most common eye diseases, cataract and presbyopia, are due to the fact that the large molecules that make up the lens do not turnover. In lenses of older people proteins, which make up the bulk of the transparent tissue, become degraded. It turns out that very long lived proteins are quite common in the body. This proposal seeks to determine what role degradation of these ancient proteins has in other diseases of aging.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: Project Grants

Funding Amount: $516,207.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

ageing | ageing population | lens | membrane lipids | protein aggregation | protein modification | vision loss

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