Defining mechanisms of androgen receptor action that impede breast cancer progression

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1008349

Funding Status
Closed

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Funded Activity Summary

Androgens (A), commonly considered male hormones, are present in women and may protect them from developing aggressive breast cancer by opposing the cancer-promoting effects of estrogen (E) hormones. We propose that a disturbance in the balance between A and E action in breast cancer worsens the disease and results in a poor outcome for afflicted women. We aim to define how A and E hormones interact in breast cancer, with a view to developing new ways to treat breast cancer and predict outcome.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $770,619.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Molecular Targets

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

androgen receptor gene expression | breast cancer | cancer progression | disease outcome | hormone therapy | hormone-dependent cancers | oestrogen receptor | steroid hormone receptors | treatment outcomes

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