The Bcl-2 life/death switch - Why do some Bcl-2 proteins kill cells whilst others promote their survival?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1008329

Funding Status
Closed

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Funded Activity Summary

The cells of all animals possess the ability to commit suicide. When this natural process of cell death is dysfunctional, diseases such as cancer arise. Our aim is to understand the molecular mechanisms that underlie this process by providing atomic resolution snapshots of key components of the cell death machinery. By understanding the fine details of cell death regulation we can develop new drugs that target and kill rogue cells such as those found in tumours.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: Project Grants

Funding Amount: $375,510.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

BAX | Bcl-2 | apoptosis | autoimmune disease | cancer | cancer biology | neurodegenerative disorders

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