Defining the cellular and molecular mechanisms underlying autoimmunity using a model of SLE

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1008288

Funding Status
Closed

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Funded Activity Summary

The immune system has to recognize the difference between foreign pathogens, which it should attack, and ourselves, which it should not. Autoimmune diseases, like lupus, occur when our immune systems attack our own tissues due to problems in regulation. We have developed an animal model of lupus that has allowed us to identify major points where immune regulation has failed. Identifying these checkpoints will allow us to design and trial novel therapeutics in lupus.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $624,960.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autoimmunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

B cells | autoantibodies | autoimmune disease | glomerulonephritis | inflammation | mouse models | signal transduction | systemic lupus erythematosus (SLE)

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