Defining the role of Activin C in gonadal and adrenal tumorigenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1008053

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Activins are members of the inhibin/TGF_ superfamily of growth and differentiation factors. Our published work implicates one of them, activin-_C as a regulator of activin A synthesis and/or its action. To test our hypothesis we will cross activin-_C over-expressing mice (ActC++ ) with inhibin a subunit knock-out mice (_-KO) that develop gonadal and adrenal tumourigenesis and is caused by increased activin A. We predict that if correct, we will prevent or delay reproductive and adrenal tumourigenesis and prolong survival.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $441,511.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Reproduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

activin | activin and inhibin | endocrinology | inhibin | testicular cancer | testis

Related Links