Role of IRF8 in central nervous system glial cell function

Funding Activity

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Funded Activity Summary

Glial cells of the brain change their function in response to local threats such as damage and this may contribute to either protection or injury of neurons. How glial cells mount this response is unknown. The goal of this project is to determine the role of the protein IRF8 in controlling the functional response of glial cells. The results will provide a better understanding of how glial cells contribute to neurological and neurodegenerative diseases.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $429,437.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

astrocytes | dementia | glial cells | interferon-gamma (IFN-gamma) | microglia | multiple sclerosis (MS) | neurodegenerative disorders | neuroimmunology | neurological disorders | signal transduction