Role of chromatid cohesion in colon biology and carcinogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1007659

Funding Status
Closed

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Funded Activity Summary

Rad21 is a gene, present in many species and essential for accurate chromosome separation and DNA damage repair. Based on its known function in different species, we predict that its� dysfunction fuels cancer progression by promoting genetic instability, which is commonly associated with human cancers. This study will use unique mouse mutant models to investigate the function of this potential cancer-causing gene in colon cancer.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $628,422.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA repair | cancer cell biology | carcinogenesis | chemotherapy | chromosomes | colon cancer | colon carcinoma | familial adenomatous polyposis (FAP) | gene expression | transcriptional regulation

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